Division for Translational and Clinical Pharmacology - Young Investigator Awards Platform and Early Career Faculty Showcase
Monday April 04, 2022
1:00 pm
-
3:00 pm
Central Time (CT)
109 AB
TCP
Chair :
Ross Corriden
Neuron23
Brandi Wynne
Univ of Utah
This session will highlight oral presentations by young scientists chosen from abstracts. Additionally, the session will feature talks from the division’s two Early Career Awardees.
Speakers
Manisha Pradhan
- Johns Hopkins University School of Medicine
Abstract #3089 - A Novel Oral Glutamate Carboxypeptidase II Inhibitor for the Treatment of Inflammatory Bowel Disease
Shubham Soni
- University of Alberta
Abstract #2891 - Ketone Therapy Reduces Systemic and Organ Inflammation in Sepsis
Piyush Padhi
- Center of Brain Science and Neurodegenerative Disease – University of Georgia
Abstract #6272 - Emerging Microbiome Genetic Engineering Technology for Stable Levodopa Delivery in Parkinson’s Disease
Shanshan Wang
- UCSD
Abstract #6305 - AAV9-synapsin-caveolin-1 (AAV9-SynCav1) Gene Delivery Preserves Motor Neuron and Neuromuscular Junction Morphology, Motor Function and Body Weight, and Extends Survival in hSOD1G93A mice
Jia Nong
- University of Pennsylvania
Abstract #5323 - Targeting Ligand Surface Density Controls both Complement Activation and Targeting Efficiency of Immunoliposomes
Klarissa Jackson
- University of North Carolina at Chapel Hill Eshelman School of Pharmacy
Studies on the Role of Metabolic Activation in Tyrosine Kinase Inhibitor-Dependent Hepatotoxicity
Metabolic activation by cytochrome P450 enzymes is proposed to play a key role in the idiosyncratic hepatotoxicity associated with several tyrosine kinase inhibitors. This lecture will highlight recent findings regarding the influence of interindividual variation in P450 activity on tyrosine kinase inhibitor metabolic activation and the implications for hepatotoxicity risk.
Jeremy Prokop
- Michigan State University
Precision Transcriptomics and Genomics to Inform Patient Treatment Options
Using thousands of patient-derived blood transcriptomes, the Prokop lab has built a robust insight into each patient's response to environmental factors, elucidating mechanisms and potential treatment options for individuals within a critical care setting.