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GPCR Colloquium

The colloquium is canceled. More information.

Colloquium on G Protein-Coupled Receptors:
Evolving Insights from Pharmacology to Physiology

Friday, April 3 - Saturday, April 4, 2020
San Diego Convention Center

Co-Chairs

Tracy M. Handel – Univ. of California, San Diego
Paul Insel – Univ. of California, San Diego
Jennifer Pluznick - Johns Hopkins Univ. School of Medicine

Tremendous scientific advancements over the last decade indicate that GPCR physiology and pharmacology is much more complex than originally thought and that it may be possible to exploit this complexity to treat a wide variety of diseases. The objective of this Colloquium is to expose scientists to recent discoveries and multidisciplinary approaches used to study GPCRs and provide opportunities for establishing collaborations that bridge complementary interests. The event will feature speakers that have made exciting discoveries in GPCR research that range from molecular to systems biology, basic research to translational studies, and pharmacology to physiology.

Preliminary Schedule

Friday, April 3

2:00 pm – 4:00 pm

Symposium I: Systems Biology Approaches to GPCR Physiology and Pharmacology

"Multi-systems Approaches to Define Vasopressin Action"
Mark Knepper – NHLBI

"Signal Cell Analysis of GPCR Expression: Implication for Physiology and Pathophysiology"
Nina Wettschureck – Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany

"Charting GPCR Signaling Network by Unbiased Approaches"
Kirill Martemyanov – The Scripps Research Institute

"Assessment of GPCR Function Using Multiplex Approaches with Next-generation Sequencing"
Sriram Kosuri - Univ. of California, Los Angeles

4:00 pm – 5:00 pm

Keynote:
“Structural Insights into the Dynamic Process of G protein-Coupled Receptor Activation”
Brian Kobilka - Stanford University

5:00 pm – 7:00 pm

Poster Presentation and Light-Bites Reception

Saturday, April 4

8:00 am – 10:00 am

Symposium II: GPCR Structural Biology and Drug Discovery

"Molecular Basis for High-affinity Agonist Binding at the Beta1-adrenoceptor"
Chris Tate – Cambridge Univ.

"New Technologies for Structure-guided GPCR Drug Discovery"
Bryan Roth – Univ. of North Carolina

"G protein-Coupled Olfactory Receptors: Novel Insights into Responsiveness and Mechano-sensitivity"
Minghong Ma – Univ. of Pennsylvania

"Molecular Mechanisms of Biased Signaling at the Angiotensin Receptor"
Laura Wingler – Duke Univ.

10:00 am – 10:30 am

Refreshment Break

10:30 am – 12:30 pm

Symposium III: GPCRs in Pathophysiology and Pathobiology

"SIP, LPA and Their Receptors in CNS Disorders"
Jerold Chun - Sanford Burnham Prebys.

"Novel Regulatory Functions of GPCRs in Vascular Growth and Remodeling"
Kathleen Caron – Univ. of North Carolina

"Novel Peptide-activated (orphan) GPCRs: New Insights and Therapeutic Opportunities"
Willis (Rick) Samson – St. Louis Univ.

"Targeting GPCRs to Improve Obesity"
Lora Heisler – Univ. of Aberdeen

Posters

Abstract submission deadline: November 14, 2019

Poster presenters for the colloquium will be selected from abstracts submitted by November 14 to EB 2020 specifically within the GPCR Colloquium topic category (#3016-ASPET). Accepted posters will be presented at both the colloquium on Friday, April 3rd and scheduled to present during one the main EB poster sessions on Sunday-Tuesday.

Registration

This is a satellite meeting to EB 2020. The colloquium ticket fee will be in addition to your EB registration fees. To register, visit the Experimental Biology registration page and add a GPCR Colloquium ticket to your EB registration. Space is limited. Be sure to register in advance.

Registration Fees: