The Drug Metabolism and Disposition Division (DMDD) serves members with interests in all aspects of drug disposition, metabolism and transport from the molecular through the phenotypic, from in vitro to in vivo approaches, and from model systems to expression of polymorphisms in humans. Specific areas include, but are not limited to, pharmacogenetics of xenobiotic metabolism and transport, regulation of the drug metabolizing and conjugating enzymes, drug transporters, pharmacokinetics, metabolite identification, role of drug metabolism, transport and disposition in drug discovery and development, structure-function relationships of relevant enzyme systems, free radicals and reactive intermediates, metabolic mechanisms of adverse drug responses, and studies focusing on all drug-metabolizing enzymes.