Division for Drug Metabolism and Disposition - Bernard B. Brodie Award, Gillette Awards, and Junior Investigator Platform Session
Monday April 04, 2022
8:00 am
-
10:00 am
Central Time (CT)
113 C
DMDD
Chair :
Xiaobo Zhong
Univ of Connecticut
Joanne Wang
Univ of Washington
This session will feature a lecture by the 2022 winner of the Bernard B. Brodie Award as well as talks from the authors of the two best papers of 2021 from the journal of Drug Metabolism and Disposition who received the James R. Gillette Awards in pharmacokinetics (transporters) and drug metabolizing enzymes. The session will also include abstract-based oral presentations from graduate students, post-bacs, and postdocs. Submit your abstract to the Drug Metabolism and Disposition topic categories below to be considered for the platform session.
Speakers
Kenneth Thummel
- Univ of Washington
Elucidating the Function of Intestinal CYP3A: A Journey of Discovery and Clinical Importance
This presentation will highlight 25 years of research to understand the function, regulation and sources of inter-individual variability in drug disposition associated with human intestinal CYP3A enzymes.
Sara Shum
- University of Washington
Predicting Maternal-fetal Disposition of Fentanyl following Intravenous and Epidural Administration using Physiologically-based Pharmacokinetic Modeling
Sisi Feng
- Shanghai Institute of Materia Medica, China
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
Shida Qian
- Shanghai Institute of Materia Medica, China
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
Deepak Ahire
- Washington State University
Abstract #3819 -Proteomics-informed Physiologically-based Pharmacokinetic (PBPK) Modeling Revealed Differential Effects of UGT2B17 Variability on the Pharmacokinetics of Diclofenac Following Intravenous and Oral Administration
Nina Nauwelaerts
- KU Leuven
Abstract #2039 - Physiologically Based Pharmacokinetic (PBPK) Modelling to Predict Breast Milk Exposure of Valproic Acid
Natalie Jay
- University at Buffalo
Abstract #3375 -Characterization of a Cleavable Fusion of Human CYP24A1 with Adrenodoxin Reveals the Variable Role of Hydrophobics in Redox Partner Binding
Zeyuan Wang
- Temple University
Abstract #2200 -Investigation of Diazepam Sequential Metabolism with Hepatocytes via a Microfluidic Device