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Targeting Adipose Inflammation in Diabetic Vascular Complications

Monday April 08, 2019

8:00 am - 10:00 am Eastern Time (ET)

Room W206 A

CVP DDD

Chair :

Rhian Touyz
University of Glasgow

Ahmed El-Yazbi
The American University of Beirut



Vasculoprotective pleiotropic effects of anti-diabetic drugs have received a lot of attention since the emergence of recent clinical data describing significant cardiovascular risk reduction in diabetic and/or prediabetic patients treated with certain molecules independent of their hypoglycemic effect. This symposium explores the detrimental role that adipose tissue inflammation plays in the development cardiovascular complications of diabetes. Recent findings regarding signaling pathways underling this deleterious interaction will be presented. Several potential therapeutic targets will be explored, together with novel therapeutic tools currently under clinical investigation. As well, new protective mechanisms for traditional drugs via modulation of adipose inflammation will be highlighted.

Speakers

Michael Czech - University of Massachusetts Medical School

Adipose Inflammation in Pre-diabetes and Insulin Resistance

Rhian Touyz - University of Glasgow

Detrimental Signaling from Dysfunctional Adipose Tissue to Vasculature

Allyson Palmer - Mayo Clinic College of Medicine and Science

Metabolic Disease and Adipose Tissue Senescence: Potential Interventions in Diabetes

Ahmed El-Yazbi - The American University of Beirut

Adipose Tissue Inflammation and Vascular Dysfunction Preceding Hyperglycemia: Modulation by Anti-Diabetic Drugs

Gavin Oudit - University of Alberta

Therapeutic Targets in Adipose Tissue in Obesity Related Heart Failure with Preserved Ejection Fraction

Last Updated: August 15, 2019
Key Dates
April 6

ASPET Business Meeting and Awards Presentation

April 6-9

ASPET Annual Meeting at EB 2019