An Apel(-in) a Day Keeps Cardiovascular Disorders at Bay?
Saturday April 06, 2019
11:00 am
-
1:00 pm
Eastern Time (ET)
Room W206 A
CVP
DDD
MP
Chair :
Hyung Chun
Yale University
Rangan Maitra
RTI International
The apelin receptor system has recently emerged as an exciting new drug target. Come learn about the fascinating journey of this GPCR from the bench to the bedside at this symposium. The apelin receptor is an important player in various types of cardiovascular diseases including heart failure, metabolic syndrome and preeclampsia. Major pharmaceutical companies have recently initiated clinical trials targeting this receptor system. An international panel of experts will present cutting-edge research from their laboratories with an eye on drug development using peptides and small molecules.
Speakers
Hyung Chun
- Yale University
Cardiometabolic Role of APJ
Bruno Reversade
- Institute of Molecular and Cellular Biology, A*STAR, Singapore
The Elabela-Ergic Pathway: From Pluripotency to Preeclampsia
Rangan Maitra
- RTI International
Biased APJ Ligands for Heart Failure
Isabelle Castan-Laurell
- INSERM U1048 I2MC
The Apelinergic System in Type 2 Diabetes: From Bench to Bedside
Liliya Yamaleyeva
- Wake Forest University School of Medicine
Hemodynamic Effects of Apelin in Preeclampsia
Carl White
- University of Nottingham
Using CRISPR/Cas9 and NanoLuc to Investigate ‘Endogenous’ CXCR4 Ligand Binding, Internalisation and
β-arrestin2 Recruitment