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Drug Metabolism and Disposition Highlighted Trainee Author for the January 2025 Issue

January 29, 2025

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Chukwunonso Nwabufo, is Drug Metabolism and Disposition Highlighted Trainee Author for the January 2025 issue. Chukwunonso is in his final year as a PhD candidate at the University of Toronto. 

The DMD article that earned him the selection as a Highlighted Trainee Author is titled “Uncovering the Impact of COVID-19–Mediated Bidirectional Dysregulation of Cytochrome P450 3A4 On Systemic and Pulmonary Drug Concentrations Using Physiologically Based Pharmacokinetic Modeling” and is available at https://doi.org/10.1124/dmd.124.001893.  

His research focuses on understanding how diseases like COVID-19 interfere with the body's ability to process drugs by altering the function of genes and proteins involved in drug metabolism and transport. His long-term career and research plans are focused on advancing personalized medicine, particularly by improving how we understand and manage disease-drug interactions. 

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