Division for Behavioral Pharmacology
Undergraduate Students
R2679, “The Hsp90 Isoform-Selective Inhibitor KUNG65 Enhances Opioid Anti-Nociception while Reducing Tolerance.” Chou, Kerry, University of Arizona
R4174,
“Strain Differences in the Delta Opioid Receptor Agonist Properties of the Multifunctional Opioid Glycopeptide MMP2200.” Connolly, Jenna, University of Michigan
R3577,
“Estradiol-Specific Neural Regulation of Social Stress Susceptibility in Female Rats.” Mott, Sarah, University of South Carolina School of Medicine
R2568, “Sex
differences in psychostimulant effects at the dopamine transporter.” Tat, Jennifer, Vanderbilt University
Graduate and Post-baccalaureate Students
R4671, “Rate of Onset as a Determinant of Abuse Potential Assessment Using Intracranial Self-Stimulation in Rats.” Baird, Tyson, Virginia Commonwealth University
R3343,
“Eating a High Fat Diet Enhances Sensitivity of Rats to Serotonin Syndrome.” Beltran, Nina, The University of Texas at El Paso
R3083, “Delta Opioid Receptor
(DOR) Agonist Activity of Buprenorphine in Mice.” Burgess, Gwendolyn, University of Michigan
R2853, “Early Chronic Methamphetamine Exposure Induces Cognitive Impairments
and Oxidative Damage in Adult Mice.” Davis, Delaney, University of North Texas Health Science Center
R2325, “Assessment of Monoacyglycerol Lipase Inhibition for
Acute and Chronic Antinociception in a Behavioral Battery for Testing Candidate Analgesics in Mice.” Diester, Clare, Virginia Commonwealth University
R1637, “MDPV
High-responder Phenotype as a Tool to Evaluate Candidate Medications for Stimulant Use Disorder.” Doyle, Michelle, University of Texas Health Science Center at San Antonio
R2618,
“Kappa-Opioid Receptors Modulate Innate and Learned Responses to Positive and Negative Reinforcers.” Farahbakhsh, Zahra, Vanderbilt University
R4294, “Interactions
Between Mu Opioid Receptor Agonists in Rats Discriminating Fentanyl.” Flynn, Shawn, University of Texas Health Science Center at San Antonio
R4646, “Methamphetamine-induced
conditioned place preference in male rats eating standard or high fat chow.” Galindo, Kayla, The University of Texas of El Paso
R3412, “Social Rank, Behavioral Phenotypes
and Kappa Opioid Receptor: PET Imaging Studies of Socially Housed Female and Male Monkey Models of Cocaine Use Disorder.” Johnson, Bernard, Wake Forest School of Medicine
R4273,
“Hyperbaric Oxygen Therapy Reversed Cognitive Deficits in a Murine Model of Alzheimer’s Disease.” Mensah Kane, Paapa, UNTHSC
R3070, “Identification of
Plasma Biomarkers Involved in Regulation of Inflammatory Pain.” Merritt, Christina, University of Texas Medical Branch
R3846, “Relationship between cognitive performance
and social rank in male and female cynomolgus macaques: implications for the role of cognition in vulnerability to cocaine use disorder.” Norman, Christina, Wake Forest School of Medicine
R3075, “Pharmacological Targeting of Microglia to Regulate Stress Susceptibility.” Pope, Brittany, University of South Carolina
R294, “A
novel rodent accelerometer device for measuring locomotor activity and other movements.” Rysztak, Lauren, University of Michigan
R1950, “Role of Efficacy as a Determinant
of Locomotor Activation Induced by Mu Opioid Receptor Ligands in Male and Female Mice.” Santos, Edna, Virginia Commonwealth University
R3781, “Evaluation of Serotonin
5-HT1A, 5-HT2A, and 5-HT2C Receptors and the Serotonin Transporter in an Fmr1 Knockout Mouse Model of Fragile X Syndrome.” Saraf, Tanishka, Mercer University
R421, “Impact
of Extended Access Methamphetamine, Cocaine, and MDPV Self-administration on Recognition Memory in Rats.” Seaman, Jr., Robert, UT Health San Antonio
R2135, “The Role
of Peripheral Opioid Receptors in the Development of Tolerance to Mu-Opioid Receptor Agonists.” Sears, Bryan, University of Michigan
R1911, “Selective MT2 Melatonin
Receptor Antagonist Modulates Circadian Activity via Inhibition of the Endogenous Melatonin Signal in the East Bound Jet Lag Model.” Sosa, Jennifer, University at Buffalo
Division for Cancer Pharmacology
Graduate and Post-baccalaureate Students
R3373, “Effects of Lysophosphatidic Acid Receptor and Free Fatty Acid Receptor Agonists on CCN1/Cyr61 Expression in Prostate Cancer Cells.” Balijepalli, Pravita, Washington State University
R3731, “SERCA Inhibition as a Potential Therapeutic Target for Breast Cancer.” Colomer-Saucedo, Jesika, Southern Illinois University, Carbondale, School of Medicine
R2910, “Mad1 Upregulation in Breast Cancer: Causes & Consequences.” Copeland, Sarah, University of Wisconsin, Madison
R1836, “Assessing
CCR1 Antagonists for Chemotaxis Inhibition in a Multiple Myeloma in vitro Model.” Echeverria, Stephanie, Midwestern University
R2115, “Potential of Pharmaceutical
Intervention in Platelets and Cancer Positive Feedback Loop.” Isingizwe, Zitha Redempta, University of Oklahoma Health Sciences Center
R2914, “A clinically relevant
combination treatment of doxorubicin and cyclophosphamide does not induce hepatotoxicity in C57BL/6J mice.” Salamat, Julia, Auburn University
R4625, “Repurposing
an Antiepileptic Drug for the Treatment of Glioblastoma.” Yadav, Anjali, St. John's University
Postdoctoral Scientists
R2906, “Deciphering the
Mechanisms of Action of Altertoxin II in Ewing Sarcoma.” Robles, Andrew, Greehey Children's Cancer Research Institute, UT Health San Antonio
Division for Cardiovascular Pharmacology
Undergraduate Students
R2169, “Differential GRK Recruitment and the Phosphorylation Barcode as a Mechanism for Biased Agonism at G Protein-Coupled Receptors.” Gardner, Julia, Duke University
R2187, “In Vitro Acute Ischemic Injury Altered Human Brain Endothelial MMP-9 Activity and Associated Cell Surface Adhesion Protein Expression in Part by S1PR Type 1 Activation.” Sin, Kristina,
University of Arizona College of Medicine, Phoenix
Graduate and Post-baccalaureate Students
R176, “Malate Ameliorates Unilateral Ureter Obstruction (UUO)-Induced Nephropathy Through
Stimulation of Nuclear Factor Erythroid-2 (Nrf2) and its Related Genes.” Edosuyi, Osaze, University of Benin
R3581, “Endothelial P2Y2-mediated vasoconstriction
is inhibited in middle cerebral arteries of rabbits treated with clopidogrel.” Kuszynski, Dawn, Michigan State University
R1988, “Loss of Salt
GlucocorticoidKinase (SGK) 1 in T cells abrogates Memory T Cell Formation, Hypertension and End-Organ Damage.” Maaliki, Dina Salem, American University of Beirut
R2884,
“GRK5-Dependent p53 Activity Controls Basal Cardiac Function and Survival.” Marzano, Federica, Temple University
R3178, “In Vivo Endothelial NO Activation by
Losartan Is Independent of Blood Pressure Lowering and EXP3179/EXP3174 Metabolites Yet Require First Passage Metabolism.” Sauge, Elodie, University of British Columbia
R2423,
“Genetic deletion of soluble epoxide hydrolase preserves cardiac function and limits inflammation in acute lipopolysaccharide injury.” Sosnowski, Deanna, University of Alberta
R3686,
“Ozanimod Preserves Endothelial Health by Attenuating Cerebrovascular MMP-9 Activity Following Acute Ischemic Injury.” Wendt, Trevor, University of Arizona College of Medicine, Phoenix
Postdoctoral Scientists
R4465, “Investigation of the Mechanistic Impact of Prenatal Exposure to Thirdhand Smoke on Platelet Activation.” Alarabi, Ahmed, Texas A&M University
R4727,
“Cardiomyocyte NLRP3 Contributes to the Cardiac Inflammatory Response.” Ninh, Van, University of California San Diego
Division for Drug Discovery and Development
Undergraduate Student
R1938, “Sympathetic and Parasympathetic Regulation of NF-κB by GPCRs through the modulation of interactions between p65/RelA and the β-arrestins.” Honeycutt, Christopher,
Duke University
Graduate and Post-baccalaureate Students
R1643, “Evaluation of the Terpenes β-caryophyllene, α-terpineol, and γ-terpinene in the Mouse Chronic Constriction
Injury Model of Neuropathic Pain: Possible Cannabinoid Receptor Involvement.” Ortiz, Yuma, University of Florida, College of Pharmacy
R2466, “Optimization of ML321:
a D2 dopamine receptor-selective antagonist for the treatment of neuropsychiatric disorders.” Rocereta, Julia, National Institute of Neurological Disorders and Stroke
R2170,
“Natural and Synthetic Cannabinoids Reduce Cell Viability of Ewing Sarcoma TC-71 Cells Potentially via Non-canonical CB receptors.” Shoeib, Amal, University of Arkansas for Medical Sciences
R3944, “Bromodomain-Containing Protein 4 (BRD4) Inhibitors as Emerging Therapeutics for Opioid Use Disorder.” Silva, Jacqueline, University of Texas Medical Branch
R3130, “Mass Spectrometry-Based Proteomic Profiling of Efavirenz-, Nevirapine-, and Acetaminophen-Induced Toxicity in Primary Human Hepatocytes.” Yuan, Yuting, Johns Hopkins School of Medicine
Postdoctoral Scientists
R2288, “In vivo Hepatoprotective Effect of Combretum micranthum Leave Extract.” Adebisi, Iyabo, Usmanu Danfodiyo University, Sokoto, Nigeria
R3368, “Discovery of Small Molecule Modulators targeting Secretin
Receptors.” Dengler, Daniela, SBP Medical Discovery Institute
R3679, “Intersectional Screening Identifies Synergistic Combinatorial Therapies for Merkel Cell Carcinoma.”
Garman, Khalid, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health
R299, “Gas Chromatography-Mass Spectrometry Analysis
and Antiulcerogenic Activity of n-Butanol Fraction of Balanites aegyptiaca L Delile.” Ugwah-Oguejiofor, Chinenye, Usmanu Danfodiyo University, Sokoto, Sokoto State, Nigeria
R3597,
“SARS-CoV-2 main protease inhibitory efficacy of natural peptidic α-hydroxy amides for therapeutic applications of COVID-19.” Yarla, Nagendra, The University of Oklahoma Health Sciences Centre
Division for Drug Metabolism and Disposition
Graduate and Post-baccalaureate Students
R3285, “Inter-individual variability and differential tissue abundance of mitochondrial amidoxime reducing component 1 (mARC1) enzyme in human.” Ahire, Deepak, Washington State University
R286, “An injured liver caused by overdose of acetaminophen has altered expression and activities of P450 enzymes and associated drug efficacy during liver recovery and regeneration.” Bao, Yifan,
University of Connecticut
R3121, “Understanding the Cytochrome P450-Catalyzed Metabolism of Cannabidiol and the Implications for Hepatotoxicity.” Beers, Jessica,
University of North Carolina at Chapel Hill
R2029, “Investigations on the Oral and Brain Uptake Mechanisms of D- and L-eflornithine in the Rat.” Boberg, Mikael, University of Gothenburg, Sweden
R4065, “Protein/Protein Interactions in the Human Cytochrome P450 System.” Burris-Hiday, Sarah, University of Michigan
R1859, “YAP-TEAD mediates
peroxisome proliferator-activated receptor α- induced hepatomegaly and liver regeneration in mice.” Fan, Shicheng, School of Pharmaceutical Sciences, Sun Yat-Sen University
R2486,
“Renal Transporter Expression Changes in Rodent Models of Nonalcoholic Steatohepatitis.” Frost, Kayla, University of Arizona
R2991, “Identification of a Disordered
Region-Targeting Motif in Cytochromes P450.” Fuchs, Robert, Louisiana State University Health Sciences Center New Orleans
R2988, “In vitro Characterization of Efficacy and Toxicity of Nevirapine
Analogs as Substitutes in HIV Treatment.” Hicks, Emily, University of Colorado Anschutz
R2928, “Adrenodoxin and Substrate Binding Modulate the Vitamin-D Metabolizing
Human Cytochrome P450 24A1.” Jay, Natalie, University at Buffalo
R1524, “Gut Microbiota Modulate the Efficacy of Angiotensin-converting Enzyme Inhibitor Captopril.”
Kyoung, Jun, University of Toledo
R2092, “Metabolism of HER2-Selective Kinase Inhibitor Tucatinib in Human Liver Fractions.” Latham, Bethany,
University of North Carolina, Chapel Hill
R3461, “Naturally-Occurring Mutations to Muscle-Type Creatine Kinase Differentially Impact Canonical and Pharmacological Activities in Vitro.” Mosher,
Eric, Johns Hopkins University School of Medicine
R2038, “Role of the Proximal Region of CYP1A2 in the Homomeric P450 Complex Formation.” Saha, Aratrika,
LSUHSC
R3282, “Analysis of Monoamine and Organic Cation Transporter Expression in Neuroblastoma and Relationship with Overall Survival.” Salvador Vieira, Leticia,
University of Washington
R2185, “Characterization of a Novel HEK293 Cell Line (HEK293-ENT1KO) to Assess the Role of Equilibrative Nucleoside Transporter Subtype-2.” Shahid, Nayiar,
University of Alberta
R372, “Does fed-state associated prolonged gastric emptying affect drug transport kinetics in intestine?” Sharma, Sheena, Washington State University Spokane
R3284, “Fluconazole Protects against Abdominal Aortic Constriction-Induced Cardiac Hypertrophy.” Shoieb, Sherif M., University of Alberta, Edmonton
R4197,
“Evaluation of Large Organic Anion Transport at the Blood-CSF Barrier by Quantitative Fluorescence Microscopy.” Sun, Austin, University of Washington
R3511, “Glucuronidation
of Efavirenz and its Cytochrome P450-dependent Metabolites in Brain Microsomes and Neurons.” Wheeler, Abigail, Johns Hopkins University School of Medicine
R2177, “Development
of a High-throughput Fluorescent-Based Assay to Assess Cytochrome P450 CYP3A7 Activity in Neonatal Human Liver Microsomes.” Work, Hannah, University of Colorado, Skaggs School of Pharmacy
Postdoctoral Scientists
R3854, “Can Cannabinoids Precipitate UGT-mediated Drug Interactions?” Bansal, Sumit, University of Washington, Seattle
R304, “Structural and Functional
Insights into Aldosterone Biosynthesis.” Brixius-Anderko, Simone, University of Michigan
R3022, “Physical Interactions between Heme Oxygenase-1 and the Cytochromes
P450 Lead to Complex Changes in Enzyme Activity.” Connick, John, LSUHSC
R2733, “Human Renal Xenobiotic Transporter Expression is Altered in Progression of Non-Alcoholic
Fatty Liver Disease as revealed by Quantitative Targeted Proteomics.” Jilek, Joseph, University of Arizona, College of Pharmacy
R3549, “Deciphering allosteric coupling
between substrate binding and redox partner recognition in rat CYP24A1, a Vitamin-D C-24 hydroxylase.” Kumar, Amit, University at Buffalo
R1758, “Proteomics-Informed
Scaling of Irinotecan Metabolism, Transport, and Gut Microbial Activation Explain its Intestinal Toxicity after Intravenous Dose.” Parvez, Md Masud, Washington State University
R2825,
“The Enzymatic Activities of Nucleoside Triphosphate Diphosphohydrolases Towards Tenofovir Diphosphate and Their Spatial Distributions in Human Colorectal Tissue.” Seneviratne, Herana, Johns Hopkins University School of Medicine
R2588, “Expression and Characterization of P. aeruginosa Cytochrome P450 CYP168A1.” Tooker, Brian, University of Colorado, Skaggs School of Pharmacy
Division for Molecular Pharmacology
Graduate and Post-baccalaureate Students
R2941, “The PKC-δ/ NF-κB/p300/TNFα signaling cascade and HDAC activity facilitate LPS-induced Rgs10 silencing in pulmonary macrophages.” Almutairi, Faris, University of Georgia
R1814, “Selective or Specific M1 Muscarinic Receptor Antagonists Exhibit Biased Agonism at the M1 Receptor via β-arrestin Signaling.” Amiri, Shayan, University of Manitoba
R2393, “Deciphering the Novel Role of Gαz in Mu Opioid Receptor Signaling.” Barnett, Miriam, University of Rochester
R2144, “Role of
β-arrestin Isoforms in Delta Opioid Receptor Agonist-Induced Seizures.” Blaine, Arryn, Purdue University
R2580, “The Spatiotemporal Bias in Proinflammatory p38
Signaling Revealed by a Forster’s Resonance Energy Transfer (FRET)-based Platform for Mapping GPCR-induced Vascular Inflammation.” Burton, Jeremy, University of Georgia
R2138,
“Identification of PDZ‐RhoGEF (PRG) as a Novel Gαi Target.” Chandan, Naincy, University of Michigan School of Medicine
R2684, “Molecular insight into
the outside-in activation of integrin αvβ3 by 24(S)-hydroxycholesterol.” Chen, Justin, Washington State University
R2238, “Deubiquitinases as Regulators
of Thrombin-induced p38 Inflammatory Response.” Cheng, Norton, University of California, San Diego
R4077, “Deficiency in Protein Kinase D Activity exacerbates post-stroke
injuries and impairs functional recovery after ischemic stroke in Mice.” Connelly, Jaclyn, University of Pittsburgh
R2908, “A Conserved Extracellular Motif Regulates
Signaling and Trafficking of ADGRG2.” Gad, Abanoub, University of Maryland, Baltimore
R4254, “Optical Interrogation of Metabotropic Glutamate Receptor-Mediated Modulation
of Cortical Circuits using Optimized Photoswitchable Tethered Ligands.” Gutzeit, Vanessa, Weill Cornell Medicine
R2632, “Regulator of G-protein signaling 14 (RGS14)
alters hippocampal pathology following excitotoxic injury due to status epilepticus.” Harbin, Nicholas, Emory University
R4164, “The N40D Variant Presents Distinct
Trafficking and Signaling Properties to the Mu-Opioid Receptor.” Hernandez-Casner, Caroline, University of Michigan
R2252, “A Structural Study of G protein Selectivity
in the Muscarinic Acetylcholine Receptor Family.” Jaimes Santiago, Luis, California State University Northridge
R4474, “Investigating pY240-PTEN:Ki-67 Interaction
and its Role in DNA Damage Response.” Jones, Brandon, University of California, San Diego
R4123, “Proton-gated coincidence detection is a common feature of GPCR signaling.”
Kapolka, Nicholas, University of Miami Miller School of Medicine
R4650, “Structural Studies and Dynamics of p90 Ribosomal S6 Kinase (RSK).” Kobori,
Evan, University of California, San Diego
R2003, “Signaling Specificity of the Gαi G Protein Subfamily 8.5.5.” Lefevre, Tyler, University of Michigan
R3001, “Structural Determination of the CCT:Gβ5 folding intermediate.” Ludlam, William, Brigham Young University
R2503, “Identification
of a Novel δOR Selective Agonist Chemotype, Notably Devoid of a Basic Nitrogen.” Meqbil, Yazan, Purdue University
R4653, “Endocytic trafficking and signaling
of proton-sensing receptor GPR65.” Morales-Rodriguez, Loyda, University of Michigan Ann Arbor
R2911, “Understanding molecular mechanism of PLCe regulation by small
G-proteins.” Muralidharan, Kaushik, Purdue University
R4255, “Bi-directional cAMP signaling crosstalk between dopamine D2 receptors and the constitutively active
orphan receptor GPR52.” Murphy, Ryan, University of Texas Medical Branch
R4144, “Allosteric modulation of cannabinoid receptors through transmembrane binding sites
as a potential therapeutic intervention for pain and inflammation.” Obi, Peter, Washington State University
R2477, “Elucidating the Role of Insulin-induced AKR1C3
and the 11-oxygenated Androgens in Promoting the Androgen Excess of Polycystic Ovary Syndrome (PCOS).” Paulukinas, Ryan, University of Pennsylvania
R2376, “Role of
sorting nexin adaptor proteins in GPCR regulation.” Robleto, Valeria, Medical College of Wisconsin
R3636, “Characterization of p38 Inflammatory Response in Human
Brain Vascular Pericyte Cells.” Roos, Morgan, University of Georgia
R1986, “The Molecular Evolution and Mechanism of Proton-sensing GPCRs.” Rowe,
Jacob, University of Miami Miller School of Medicine
R1890, “Spatial Compartmentalization of mTORC1 to the Outer Mitochondrial Membrane to Regulate Mitochondrial Metabolism.” Sahan,
Ayse, University of California, San Diego
R4181, “Synergistic Activation of PLC-dependent Diacylglycerol (DAG) Production by Mu-Opioid and Gq-Coupled Receptor Signaling.” Sanchez,
Gissell, University of Michigan
R2476, “A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling.” Semesta, Khairunnisa,
Duke University
R1872, “Chloroquine ameliorates hind-limb ischemia/reperfusion-induced remote hepatic injury via attenuating p38-Mapk/NF-κB p65 cue.” Sherif, Miar,
Egyptian Drug Authority
R3627, “Structural Insights and Characterization of a Novel Transmembrane Binding Site for Potential Allosteric Modulation of the Mu-opioid Receptor.” Szlenk,
Christopher, Washington State University
R3685, “Selective Targeting of Calcineurin Isoforms by Calcineurin Inhibitors.” Ume, Adaku, Wright State University
R2961, “G Protein-Coupled Receptor Kinase 6 (GRK6) Regulation of Insulin Processing and Secretion.” Varney, Matthew, Thomas Jefferson University
R4392,
“Discovery of Small Molecule Adhesion GPCR Modulators.” Vizurraga, Alexander, University of Michigan
R4171, “G Protein-Coupled Receptor Regulation of the alpha-Arrestin
ARRDC3.” Wedegaertner, Helen, University of California, San Diego
R1605, “Membrane Lipids and Cellular Water Modulate the G-Protein–Coupled Receptor Activation.”
Weerasinghe, Nipuna, University of Arizona
R2563, “Golgi-resident β1-adrenergic Receptor Signaling to Cardiac Hypertrophy in Cardiac Myocytes in Vitro and in Failing
Hearts in Vivo.” Wei, Wenhui, University of Michigan
R3531, “Approaches to Dissect the Role of Endosome Positioning in Spatially Encoded GPCR Signaling.” Willette,
Blair, Duke University
R3788, “Pharmacological profiles of 5-HT2A Receptor (5-HT2AR):5-HT2CR Interactions In Vitro.” Zamora, J., University of Texas Medical Branch
Postdoctoral Scientists
R2200, “GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11.” Abboud, Dayana, University of Liege
R2339,
“Molecular Mechanism of GPCR-mediated ERK Pathway in Cancer.” Kwon, Yonghoon, University of California, San Diego
R3870, “Location Bias in cAMP Signaling and
its effects on Parathyroid Hormone Receptor Biological Effectiveness.” Pena, Karina, University of Pittsburgh
R3060, “XLαs is a novel activator of PLCβ4.”
Phan, Hoa, University of Michigan
R2799, “G protein-coupled receptor kinase 2 can enhance β-arrestin recruitment to the D2 dopamine receptor in the absence of receptor
phosphorylation.” Sanchez Soto, Marta, NINDS/NIH
R3785, “Cryo-EM Structure of Atypical Chemokine Receptor 3 (ACKR3) in Complex with its Endogenous Ligand CXCL12.”
Yen, Yu-Chen, Purdue University
Division for Neuropharmacology
Undergraduate Students
R4258, “Microglial regulation of social stress susceptibility in Female Rats.” Augenblick, Lee, University of South Carolina School of Medicine
R3982,
“Cocaine Self-administration Modulates Brain Ceramide Metabolism.” Major, Alexander, Wake Forest University
R3036, “A Low Dose of Loperamide Restores Normal
Activity Without Disruptive Side Effects in Rats with Chronic Inflammatory Pain.” Ouyang, Lisa, California State University, East Bay
R3294, “Analysis of Formalin-depressed
Wheel Running and its Reversal by Ketoprofen.” Quintana, Taylor, California State University, East Bay
Graduate and Post-baccalaureate Students
R3888, “Loss of Nociceptin/Orphanin FQ peptide receptor protects against traumatic brain injury (TBI)-induced deficits in male and female rats.” Al Yacoub, Omar, University of Oklahoma Health Sciences Center
R3016, “PMAT Deficiency Sex-Selectively Contributes to Cocaine and Amphetamine Locomotor Sensitization.” Beaver, Jasmin, Kent State University
R2474,
“Persistent Inflammation Reduces Cannabinoid 1 Receptor Function in the Ventrolateral Periaqueductal Gray.” Bouchet, Courtney, Oregon Health & Science University
R154,
“Inhibition of cAMP-Phosphodiesterase 4 (PDE4) Induces Salivation in Mice.” Boyd, Abigail, University of South Alabama
R2465, “Pharmacological Characterization
of Synthetic Kratom Alkaloids for Improved Alcohol Use Disorder Therapeutics.” Gutridge, Anna, Purdue University
R4155, “High Salt Intake Increases Contextual Fear
Retrieval and Synaptic Inhibition of Medial Entorhinal Cortex-Projecting Neurons of the Basolateral Amygdala.” Hammack, Robert, University of Texas Health Science Center at San Antonio
R3244,
“Examining Sex Differences in Response to NMDAR Antagonist MK-801 on Sleep Architecture and Brain Function Using Electroencephalography in Rats.” Holter, Kimberly, Wake Forest School of Medicine
R3809, “Ablation of optineurin impairs metabotropic glutamate receptor 5 signaling in mouse hippocampus.” Ibrahim, Karim, University of Ottawa Brain and Mind Research Institute
R3937, “Chronic Morphine Exposure and μ-opioid Receptor Phosphorylation Deficiency Enhances Opioid Sensitivity of Thalamo-Striatal Synapses.” Jaeckel, Elizabeth, University of Michigan
R2019, “Response to Novelty Predicts α7 Nicotinic Receptor and Voltage-Gated Calcium Channel Modulation of Dopamine Release.” Leach, Amy, Wake Forest School of Medicine
R4642, “Characterizing the Effect of Clodronate in the Locus Coeruleus During Social Stress.” Martinez-Muniz, Gustavo, University of South Carolina School of Medicine
R1699, “Fentanyl, but not Morphine, Increases Cortical Electroencephalographic (EEG) Delta Power during Wakefulness in C57BL/6J (B6) Mice.” O'Brien, Christopher, University of Tennessee - Knoxville
R3524, “Effects of Non-contingent and Self-administered Oxycodone on Sleep Architecture in Rats.” Pierce, Bethany, Wake Forest School of Medicine
R3935,
“Protein Kinase-C Inhibition Within the Periaqueductal Gray Counteracts the Development of Morphine Antinociceptive Tolerance.” Ram, Akila, Utah State University
R2201,
“Time-of-Day Variation in Learning, Reward-Associated Behaviors, and Rapid Dopamine Release.” Stowe, Taylor, Wake Forest School of Medicine
R3928, “Accumbal
D1 and D2 medium spiny neurons control distinct learning parameters in complex behavior.” Zachry, Jennifer, Vanderbilt University
R1706, “Fentanyl and Morphine Cause
Dose-Dependent Sleep Disruption in C57BL/6J (B6) Mice.” Zebadua Unzaga, Diana, University of Tennessee, Knoxville
Postdoctoral Scientists
R4080, “Oleamide Analogues as Positive Allosteric Modulators of the Serotonin (5-HT) 5‑HT2C and 5‑HT2A Receptors.” Chen, Jianping, The University of Texas Medical Branch
R1793,
“Selective mGlu1 potentiation enhances cortical inhibition to rescue schizophrenia-like cognitive and social deficits.” Luessen, Deborah, Vanderbilt University
R3733,
“Impact of Cell Membrane Cholesterol Alterations on Function, Oligomerization, and Binding Affinity of Monoamine Transporters.” Rudin, Deborah, Medical University of Vienna
Division for Pharmacology Education
Graduate and Post-baccalaureate Students
R2587, “A Virtual Platform for Teaching ACLS Pharmacology to Undergraduate Medical Students.” Conway, Nicholas, Herbert Wertheim College of Medicine, Florida International University
R2522, “Real-Time Virtual Naloxone Training for Fourth Year Medical Students.” Ehrhardt, Tori, Herbert Wertheim College of Medicine, Florida International University
R2584, “Pharmacologic Management and Treatment of Osteoporosis: A Small Group Case-Based Learning Activity.” Nguyen, Bianca, Herbert Wertheim College of Medicine, Florida International University
Division for Toxicology
Undergraduate Students
R3896, “Farnesoid X Receptor Regulates Immune Cell Activation and Recruitment to the Lung following Exposure of Mice to Nitrogen Mustard.” Banota, Tanvi, Rutgers University
R2737, “Immunomodulatory effects of Brominated Flame Retardants on Cytokine Production in Mast cells.” King, Ethan, Western New England University
Graduate and Post-baccalaureate Students
R4195, “Development of Feed Forward and Conditional Models Based on Rodent Imaging Data to Predict Effects of Nitrogen Mustard on Pulmonary Function.” Andres, Jaclynn, Rutgers University
R4116, “RNA Sequencing Reveals Differential Mechanisms of Brominated Flame Retardant Nephrotoxicity That Are Chemical and Cell Line-Specific.” Barnett, Lillie, University of Georgia
R4408, “The Evaluation of Acute Lung Injury Induced by Nitrogen Mustard in Mouse Precision Cut Lung Slices.” Bellomo, Alyssa, Rutgers University
R2102,
“Major Metabolites of the Synthetic Cannabinoid 5F-ADB Retain High Affinity and Full Efficacy at CB1 Receptors; Potential Mechanism Contributing to Enhanced Toxicity?” Cabanlong, Christian, University of Arkansas for Medical Sciences
R193, “Efficacy of Green Tea Consumption on Reducing Body Mass Index and Insulin Resistance: A Meta-Analysis.” Tan, Kaiming, DeBusk College of Osteopathic Medicine at Lincoln Memorial University-Knoxville
R2168, “Changes in Insulin Signaling and Gluconeogenic Gene Expression in Human Hepatocytes Following Exposure to Heterocyclic Amines.” Walls, Kennedy, University of Louisville School of Medicine
R1690, “Selenide stimulates the biliary excretion of arsenic in human HepaRG cells.” Zhou, Janet, University of Alberta
Postdoctoral Scientists
R2485, “Chronic Intermittent Access to Alcohol Increases Cav1.2 in Dopamine Cells of the Substantia Nigra Pars Compacta.” Rodriguez, Eric, Indiana University School of Medicine
R3987, “Phosgene Oxime Dermal Exposure Induces Inflammation, Mast Cell Activation and Oxidative stress.” Singh, Satyendra, Michigan State University
R3505,
“Rosiglitazone restores pulmonary surfactant and lipid homeostasis in mice exposed to ozone.” Smith, Ley, Rutgers University
Division for Translational and Clinical Pharmacology
Graduate and Post-baccalaureate Students
R2547, “A Pharmacokinetic Study of High-Dose Intravenous Vitamin C in Healthy Volunteers and Oncological Patients.” Chen, Ping, University of Kansas Medical Center
R3525,
“Dosing Time Optimization of Enalapril and Propranolol through Inclusion of the Circadian Rhythm in Pharmacokinetic-Pharmacodynamic Modeling.” Cortés, Javiera, Pontifica Universidad Católica de Chile
R1569, “Which QT Correction Method is Most Consistent?” Ether, Nicholas, Michigan State University
R2573, “Identifying and Validating Plasma
Circulating Renin-Angiotensin System Components as Reliable Biomarkers of Rheumatoid Arthritis.” Khajehpour, Sana, Idaho State University
R133, “Oral Bioavailability
of Deuterated L-carnitine in Healthy Volunteers.” Moutinho, Tomas, University of Campinas (UNICAMP)
Dolores C. Shockley Competition
Undergraduate Student
R3294, “Analysis of Formalin-depressed Wheel Running and its Reversal by Ketoprofen.” Quintana, Taylor, California State University, East Bay
Graduate and Post-baccalaureate Students
R3343, “Eating a High Fat Diet Enhances Sensitivity of Rats to Serotonin Syndrome.” Beltran, Nina, The University of Texas at El Paso
R2144, “Role
of β-arrestin Isoforms in Delta Opioid Receptor Agonist-Induced Seizures.” Blaine, Arryn, Purdue University
R2102, “Major Metabolites of the Synthetic Cannabinoid
5F-ADB Retain High Affinity and Full Efficacy at CB1 Receptors; Potential Mechanism Contributing to Enhanced Toxicity?” Cabanlong, Christian, University of Arkansas for Medical Sciences
R3525,
“Dosing Time Optimization of Enalapril and Propranolol through Inclusion of the Circadian Rhythm in Pharmacokinetic-Pharmacodynamic Modeling.” Cortés, Javiera, Pontifica Universidad Católica de Chile
R4164, “The N40D Variant Presents Distinct Trafficking and Signaling Properties to the Mu-Opioid Receptor.” Hernandez-Casner, Caroline, University of Michigan
R2252,
“A Structural Study of G protein Selectivity in the Muscarinic Acetylcholine Receptor Family.” Jaimes Santiago, Luis, California State University Northridge
R4642,
“Characterizing the Effect of Clodronate in the Locus Coeruleus During Social Stress.” Martinez-Muniz, Gustavo, University of South Carolina School of Medicine
R4653,
“Endocytic trafficking and signaling of proton-sensing receptor GPR65.” Morales-Rodriguez, Loyda, University of Michigan Ann Arbor
R2376, “Role of sorting nexin
adaptor proteins in GPCR regulation.” Robleto, Valeria, Medical College of Wisconsin
R4181, “Synergistic Activation of PLC-dependent Diacylglycerol (DAG) Production
by Mu-Opioid and Gq-Coupled Receptor Signaling.” Sanchez, Gissell, University of Michigan
R1950, “Role of Efficacy as a Determinant of Locomotor Activation Induced
by Mu Opioid Receptor Ligands in Male and Female Mice.” Santos, Edna, Virginia Commonwealth University
R3788, “Pharmacological profiles of 5-HT2A Receptor (5-HT2AR):5-HT2CR
Interactions In Vitro.” Zamora, J., University of Texas Medical Branch
R1706, “Fentanyl and Morphine Cause Dose-Dependent Sleep Disruption in C57BL/6J (B6) Mice.”
Zebadua Unzaga, Diana, University of Tennessee, Knoxville
Postdoctoral Scientists
R3870, “Location Bias in cAMP Signaling and its effects on Parathyroid Hormone Receptor Biological Effectiveness.” Pena, Karina, University of Pittsburgh
R2906,
“Deciphering the Mechanisms of Action of Altertoxin II in Ewing Sarcoma.” Robles, Andrew, Greehey Children's Cancer Research Institute, UT Health San Antonio
R2485,
“Chronic Intermittent Access to Alcohol Increases Cav1.2 in Dopamine Cells of the Substantia Nigra Pars Compacta.” Rodriguez, Eric, Indiana University School of Medicine
R299,
“Gas Chromatography-Mass Spectrometry Analysis and Antiulcerogenic Activity of n-Butanol Fraction of Balanites aegyptiaca L Delile.” Ugwah-Oguejiofor, Chinenye, Usmanu Danfodiyo University, Sokoto, Sokoto State, Nigeria