R353, “A novel role of ADGRF1 (GPR110) in promoting cellular quiescence and chemoresistance in human epidermal growth factor receptor 2-positive breast cancer.” Abdulkareem, Noor, University of Houston
R3689, “Apelin-Induced Relaxation is Impaired in Coronary Arteries from Spontaneously Hypertensive Rats.” Anto, Santo, North Dakota State University
R3083, “Delta Opioid Receptor (DOR) Agonist Activity of Buprenorphine in Mice.” Burgess, Gwendolyn, University of Michigan
R2102, “Major Metabolites of the Synthetic Cannabinoid 5F-ADB Retain High Affinity and Full Efficacy at CB1 Receptors; Potential Mechanism Contributing to Enhanced Toxicity?” Cabanlong, Christian, University of Arkansas for Medical Sciences
R2138, “Identification of PDZ‐RhoGEF (PRG) as a Novel Gαi Target.” Chandan, Naincy, University of Michigan School of Medicine
R3635, “Structure of the rhodopsin–rhodopsin kinase complex defines the rules of engagement between G protein-coupled receptors (GPCRs) and GPCR kinases.” Chen, Qiuyan, Purdue University
R1987, “Opioids Cause Vascular Dysfunction in a Sex-Specific Manner.” Cheon, Soyoung, University of Toledo College of Medicine and Life Sciences
R1731, “RNF8 stabilizes MYC via K63-linked ubiquitination to promote metabolic reprogramming in triple-negative breast cancer.” Chern, Yi-Jye, Stony Brook University
R2354, “Reversal of Aging-Associated Vasoreparative Dysfunction and Myelopoietic Bias in Bone Marrow Stem/Progenitor Cells by Angiotensin-(1-7).” Chittimalli, Kishore, North Dakota State University
R4584, “The Impact of Angiotensin Converting Enzyme Inhibition and/or Angiotensin Receptor Blockade on Tissue Expression of the SARS-CoV-2 Receptor ACE2 in Mice.” da Silva Moreira, Aline, National Institute of Allergy and Infectious Diseases
R2860, “Recombinant Human Proteoglycan-4 Regulates Phagocytic Activation of Monocytes and Reduces IL-1b Secretion by Urate Crystal Stimulated PBMCs.” Elsayed, Sandy, Chapman University School of Pharmacy
R4372, “Sex-Selective Impact of Transient ACE Inhibition on Angiotensin II-Induced Collagen Gene Expression.” Floyd, Dana, University of Arizona
R3032, “Structural Insights into PLCε: Discovery of an Integrated RA1 Domain and Novel Regulatory Elements.” Garland, Elisabeth, Purdue University
R3607, “Differential Reversal of the Ventilatory-Depressant Effects of Fentanyl and its Derivatives by Naloxone in Monkeys.” Gerak, Lisa, University of Texas Health Science Center at San Antonio
R3933, “Aging Human Endothelial Cells Affect Neuronal Viability and Function.” Grodzki, Ana, University of California, Davis
R3063, “Cyp19a1 is essential for macrophage function and pulmonary tissue repair following airway epithelial injury.” Han, Weiguo, University of Arizona
R2725, “Pharmacological Characterization of Mitragynine: Antinociception, Respiratory Depression, Self-Administration, Drug Discrimination, Tolerance, and withdrawal in Rats.” Hiranita, Takato, University of Florida, College of Pharmacy
R3937, “Chronic Morphine Exposure and μ-opioid Receptor Phosphorylation Deficiency Enhances Opioid Sensitivity of Thalamo-Striatal Synapses.” Jaeckel, Elizabeth, University of Michigan
R2343, “Gq signaling in adipocytes is a key regulator of systemic glucose and lipid homeostasis.” Kimura, Takefumi, National Institute of Diabetes and Digestive and Kidney Diseases
R2630, “Recombinant rod domain of vimentin binds to spike protein to block SARS-CoV-2 replication in vitro.” Lam, Fong, Baylor College of Medicine
R2939, “CYP3A7 drug-hormone Interactions in the Neonate: Adrenal Insufficiency and Low Birthweight in the HIV infected Neonate caused by Inhibition of CYP3A7 DHEA-S Oxidation by Ritonavir.” Lampe, Jed, University of Colorado, Skaggs School of Pharmacy
R2003, “Signaling Specificity of the Gαi G Protein Subfamily 8.5.5.” Lefevre, Tyler, University of Michigan
R3024, “MetMax Human Hepatocyte/HEK Cytotoxic Reactive Metabolite Assay as a Potential In Vitro Experimental System for the Identification of DILI Drugs.” Li, Albert, In Vitro ADMET Laboratories Inc.
R3224, “A genome-wide CRISPR interference screen using a novel reporter for endo-lysosomal trafficking reveals a role for RME-8 in opioid receptor regulation.” Lobingier, Braden, Oregon Health Sciences University
R1648, “Interactive Annotation Is an Effective Tool for Delivering Virtual Pharmacology Large Group Sessions.” Ma, Li, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
R1694, “Use of Novel ebBRET Biosensors for Comprehensive Signaling Profiling of One Hundred Therapeutically Relevant Human GPCRs.” Mancini, Arturo, Domain Therapeutics
R4642, “Characterizing the Effect of Clodronate in the Locus Coeruleus During Social Stress.” Martinez-Muniz, Gustavo, University of South Carolina School of Medicine
R4681, “Novel Bioactivation of Isoxazole-containing Bromodomain and Extra Terminal Domain (BET) Inhibitors.” Miller, Grover, University of Arkansas for Medical Sciences
R3405, “Nox5 in Vascular Smooth Muscle Cells Mediates Ang II-Induced Renal Fibrosis and Inflammation.” Montezano, Augusto, ICAMS - University of Glasgow
R3461, “Naturally-Occurring Mutations to Muscle-Type Creatine Kinase Differentially Impact Canonical and Pharmacological Activities in Vitro.” Mosher, Eric, Johns Hopkins University School of Medicine
R1979, “The Impact of a Pre-Medicine Pharmacology-Focussed Capstone in the Preparation of Students for Medical School.” Nirthanan, Selvanayagam (Niru), Griffith University
R3172, “Nanocarriers Targeting Intercellular Adhesion Molecule Enhance Delivery to the Inflamed Brain.” Nong, Jia, University of Pennsylvania
R470, “Identification of a novel small-molecule allosteric inhibitor of glucose transporter type 5 for treating fructose-induced diseases.” Ookawara, Mitsugi, SCOHIA PHARMA, Inc.
R2392, “GluN2B-containing NMDA Receptors on Sst-interneurons act as Initial Cellular Trigger for Antidepressant Actions of Ketamine.” Pothula, Santosh, Yale University
R2703, “Spike protein 1 of SARS-CoV-2 induces an immune and inflammatory response and increases expression of ACE2 in human endothelial cells.” Rios, Francisco, BHF-ICAMS - University of Glasgow
R2038, “Role of the Proximal Region of CYP1A2 in the Homomeric P450 Complex Formation.” Saha, Aratrika, Louisiana State University Health Sciences Center
R1950, “Role of Efficacy as a Determinant of Locomotor Activation Induced by Mu Opioid Receptor Ligands in Male and Female Mice.” Santos, Edna, Virginia Commonwealth University
R2476, “A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling.” Semesta, Khairunnisa, Duke University
R3762, “Immuno-Reactive Cancer Organoid Models to Examine Microbiome Metabolite Effects on Immune Checkpoint Blockade Efficacy.” Shelkey, Ethan, Wake Forest Graduate School
R3944, “Bromodomain-Containing Protein 4 (BRD4) Inhibitors as Emerging Therapeutics for Opioid Use Disorder.” Silva, Jacqueline, University of Texas Medical Branch
R2423, “Genetic deletion of soluble epoxide hydrolase preserves cardiac function and limits inflammation in acute lipopolysaccharide injury.” Sosnowski, Deanna, University of Alberta
R2201, “Time-of-Day Variation in Learning, Reward-Associated Behaviors, and Rapid Dopamine Release.” Stowe, Taylor, Wake Forest School of Medicine
R4001, “Intestinal Sulfation is Essential to Protect Against Colitis-Associated Colonic Carcinogenesis.” Xu, Pengfei, University of Pittsburgh
R4632, “Differential Effects of Combined Soluble Epoxide Hydrolase inhibitor t-TUCB and n-3 Epoxide in Diet-Induced Obesity.” Yang, Yang, University of Tennessee, Knoxville