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Joint Colloquium on G Protein-Coupled Receptors: Symposium I - Systems Biology Approaches to GPCR Physiology and Pharmacology

Monday May 10, 2021

12:15 pm - 2:15 pm Eastern Time (ET)



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Tremendous scientific advancements over the last decade indicate that GPCR physiology and pharmacology are much more complex than originally thought and that it may be possible to exploit this complexity to treat a wide variety of diseases. The objective of this colloquium is to expose scientists to recent discoveries and multidisciplinary approaches used to study GPCRs and provide opportunities for establishing collaborations that bridge complementary interests.

The two-day event, held May 10-11 in the EB virtual platform, will feature speakers who have made exciting discoveries in GPCR research that range from molecular to systems biology, basic research to translational studies, and pharmacology to biochemistry to physiology.

Thanks to the generosity of our sponsors and support from ASPET, ASBMB, and APS, a ticket for the colloquium is being provided at no extra charge with your paid registration to Experimental Biology.

Speakers

Mark Knepper - NHLBI

V2R-omics: Multi-systems Approaches to Define Vasopressin Action

Nina Wettschureck - Max Planck Institute for Heart and Lung Research

Single Cell Analysis of GPCR Expression: Implication for Physiology and Pathophysiology

Kirill Martemyanov - The Scripps Research Institute

Deciphering Diversity of GPCR Signaling

G Protein-Coupled Receptors (GPCRs) encode complex signals by activating a staggering range of heterotrimeric G proteins composed from one of the 16 G subunits and the repertoire of 5 G and 12 G subunits. This signal is regulated by 20 canonical members of the Regulator of G protein Signaling proteins. The talk will cover our efforts to dissect the logic, rules of engagement and purpose for this signaling diversity.

Sriram Kosuri - University of California, Los Angeles

Combining Synthesis and Multiplexed Assays to Explore Human Biology: GPCRs as a Paradigm