Division for Molecular Pharmacology Early Career Award and Postdoc Competition
Monday April 04, 2022
8:00 am
-
10:00 am
Eastern Time (ET)
111 AB
MP
Chair :
Michelle Kimple
Univ of Wisconsin-Madison
John Hepler
Emory Univ School of Medicine
This award competition features oral presentations from postdoctoral trainees selected from the submitted abstracts as well as a keynote lecture from the winner of the ASPET Division for Molecular Pharmacology Early Career Award.
Speakers
Dipak Patil
- The Scripps Research Institute
Abstract #6204 Visualizing an Orphan Receptor GPR158 and it Complex with Neuronal Regulator RGS7-Gβ5 via cryoEM
Yu-Chen Yen
- Purdue University
Abstract #3991 - Seven Structures of Atypical Chemokine Receptor 3 Reveal the Molecular Bases for its Promiscuity and Signaling Bias
Isaac Fisher
- Purdue University
Abstract #3949 Single Particle Cryo-EM Reconstruction of an Activated Gβγ-PLCβ Complex
Matthew Torres
- Georgia Institute of Technology
From m/z to Gabg: Accessing the Collective Wisdom in Proteomics to Reveal Posttranslational Governors of G Protein Signaling
The talk will focus on the development of protein bioinformatic and computational tools that revealed how Gg subunits – through phosphorylation of their intrinsically disordered N-termini – can serve as governors of Gbg signaling.
Cheng Zhang
- Univ of Pittsburgh
GPCR Structures Reveal New Insights into Receptor Pharmacology and Drug Development
Based on our crystal and cryo-EM structures of a group of chemotactic GPCRs that can promote either the onset or the resolution of inflammation with diverse ligands, I will talk about novel mechanisms of GPCR ligand recognition and activation and discuss new opportunities in drug development for inflammation-related disorders.