Division for Drug Metabolism and Disposition Okita Early Career Award Lecture, Gillette Award Lectures, and Junior Investigator Platform Session
Friday April 30, 2021
2:00 pm
-
4:00 pm
Eastern Time (ET)
View session on the EB Virtual Platform (EB registration required)
DMDD
Chair :
Robert Foti
Merck
Xiao-bo Zhong
Univ of Connecticut
This session features a lecture given by the recipient of the 2021 Richard Okita Early Career Award in Drug Metabolism and Disposition, talks from the authors of the best papers of 2020 from the journal Drug Metabolism and Disposition who received the James R. Gillette Award, as well as abstract-based oral presentations focused on drug metabolism and disposition.
Speakers
Huichang Bi
- Sun Yat-sen University and Southern Medical University
Nuclear Receptors in Hepatomegaly and Liver Regeneration: An Update
This presentation updates the activation of pregnane X receptor (PXR), peroxisome proliferator-activated receptor-α (PPARα) and constitutive androstane receptor (CAR) on hepatomegaly and liver regeneration. Mechanistically, the interactions between these nuclear receptors and yes-associated protein (YAP) signals were presented and discussed.
Shujuan Chen
- Univ. of California, San Diego
Differential Role of Liver X Receptor (LXR) α and LXRβ in the Regulation of UDP-Glucuronosyltransferase 1A1 in Humanized UGT1 Mice
Bridget Morse
- Eli Lilly and Company
Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake
Eric Mosher
- Johns Hopkins University School of Medicine
Naturally-Occurring Mutations to Muscle-Type Creatine Kinase Differentially Impact Canonical and Pharmacological Activities in Vitro
Aratrika Saha
- LSUHSC
Role of the Proximal Region of CYP1A2 in the Homomeric P450 Complex Formation
Ankit Balhara
- National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar
Comparative Proteomics Analysis of the Post-Mitochondrial Fraction (S9 Fraction) of Human Lens-Free Whole Eye and Liver
Austin Sun
- University of Washington
Evaluation of Large Organic Anion Transport at the Blood-CSF Barrier by Quantitative Fluorescence Microscopy
Yixin Chen
- UC Davis School of Medicine
Bioengineered microRNAs in the control of folate cycle related one-carbon metabolism in NSCLC metabolism