In This Section

Division for Drug Metabolism and Disposition Gillette Awards and Junior Investigator Platform Session

Tuesday April 07, 2020

4:50 pm - 6:00 pm Eastern Time (ET)

Room 16 B

DMDD

Chair :

Robert Foti
Merck

Aiming Yu
University of California-Davis



Immediately following the award lecture given by the recipient of the 2020 Bernard B. Brodie Award in Drug Metabolism, this session features talks from the authors of the best papers of 2019 from the journal Drug Metabolism and Disposition who received the James R. Gillette Award, as well as abstract-based oral presentations focused on drug metabolism and disposition.

Speakers

Drew Neavin - Garvan Institute of Medical Research

Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand–Dependent Gene Expression

Hiroyuki Kusuhara - University of Tokyo

Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters

Muhammad Erfan Uddin - The Ohio State University

Renal Tubular Secretion of Dofetilide is Dependent on MATE1 Function

Amit Kumar - Jacobs School of Medicine and Biological Science

Substrate 1,25(OH) D3 and Adrenodoxin Exert a Coordinated Change in CYP24A1 Structure

Mei-Juan Tu - UC Davis School of Medicine

Bioengineered miR-328-3p modulates SLC2A1/GLUT1-mediated glucose uptake and metabolism to exert synergistic antiproliferative effects with chemotherapeutics

Meredith McGuire - Johns Hopkins University School of Medicine

PGRMC1 Stabilizes Cytochromes P450 And Is Required for Activity In Vivo