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Cardiovascular Signaling via the G Protein-Coupled Estrogen Receptor

Tuesday April 09, 2019

8:00 am - 10:00 am Eastern Time (ET)

Room W205 BC

CVP MP

Chair :

Sarah Lindsey
Tulane University

Kim Tran
Des Moines University



The predominant female sex hormone estrogen impacts virtually all aspects of cardiovascular health. Estrogen receptors alpha and beta are classical estrogen receptors that have been extensively studied over the past several decades. The G protein-coupled estrogen receptor 1 (GPER, aka GPR30) was more recently identified and has since been implicated in numerous cardiovascular processes. This symposium will feature recent developments in GPER signaling mechanisms in the cardiovascular system, including novel findings, challenges, therapeutic applicability, and knowledge gaps. The presentations will incorporate paradigms in pharmacology, biochemistry, physiology, and pathophysiology with techniques spanning from the molecular to whole animal level.

Speakers

Sarah Lindsey - Tulane University

GPER Signaling in Vascular Disease

Kim Tran - Des Moines University

GPER: A Moderator of Cardiovascular Signaling

Mohammed El-Lakany - Alexandria University

Estrogen Receptor-α Counterbalances the Endotoxic Inflammatory Response and Associated Arterial Baroreflex Dysfunction in Ovariectomized Rats

Qingming Ding - St. Boniface Hospital Albrectsen Research Centre

Aldosterone Binding to G Protein Estrogen Receptor - GPER

Leanne Groban - Wake Forest University

Female Heart Health: Is GPER the Missing Link?

Eric Prossnitz - University of New Mexico

The Yin Yang of GPER Regulation in Cardiovascular Function