Administrative Accomplishments
- Department of Pharmaceutical Sciences, Washington State University, Spokane, WA
- Associate Professor (September 2019-present)
- Director, Industry Engagement (September 2019-present)
- Adjunct Associate Professor (June 2019-August 2019)
- Director, PRINCE (Proteomics-based Research Initiative on Non-CYP enzymes) (2019-Present)
- Department of Pharmaceutics, University of Washington, Seattle, WA
- Assistant Professor (2015-2019)
- Director, PRINCE (Proteomics-based Research Initiative on Non-CYP enzymes) (2018-2019)
- Co-director, UWRAPT (2016-2019)
- Acting Instructor and Acting Assistant Professor (2012-2015)
- Postdoc Fellow (2011-2012)
- Department of Metabolism and Pharmacokinetics, Ranbaxy Research Laboratories
- Research Associate (2006-2007)
Research Areas
My long-term goal is to develop non-invasive approaches to predict variability in drug disposition by better understanding the genetic and non-genetic mechanisms of inter-individual differences in drug metabolism, transport and pharmacokinetics. Current research in my laboratory focusses on the variability caused by drug transporters and non-cytochrome P450 enzymes. We quantify transporters, enzymes, and their endogenous substrates in human tissues and biofluids by quantitative proteomics and metabolomics approaches, and then integrate these data along with genomics information into physiologically based pharmacokinetic (PBPK) models. Such integrated approach also allows identification and validation of surrogate biomarkers of drug transporters, metabolizing enzymes, and receptors, which are particularly important for the non-invasive prediction of drug disposition and response in special populations (e.g., children, elderly, and pregnant women) in whom clinical trials are not allowed.
ASPET Activities
- DMD Division
- 2021 Annual Meeting Session Chair (2021)
- Executive Committee
- Member (2018 – 2021)
- Secretary/Treasurer (2019 – 2020)
- Best Presentation (Poster) Awards Committee Chair (2019)
- Abstract Review committee Reviewer (2018-Present)
- TCP Division
- Early Career Faculty Showcase, Award Recipient (2018)
- 2015 Annual Meeting Session Chair (2016)
- ASPET/BPS Joint Symposium, Pharmacology 2019, Edinburgh, UK (2019)
- CNPHARS-ASPET Joint Symposium on Pharmacology (2021)
Other Society Memberships/Activities
- International Society for the Study of Xenobiotics (ISSX)
- American Society for Mass Spectrometry (ASMS)
- American College of Clinical Pharmacy (ACCP)