WIP Into Shape Networking Walk
Meet at the Grand Hyatt Concierge Desk at 7:15 am
7:00 am – 8:30 am

Diversity Mentoring Breakfast
Grand Hyatt, Burhham
7:30 am – 9:30 am

Julius Axelrod Lecture  
Washington Convention Center, Room 143A/B
8:30 am- 9:20 am

Brian Kobilka, Stanford Univ.
     Structural insights into the dynamic process of GPCR activation 

Julius Axelrod Symposium:  Structural Approaches to Understanding GPCR Signaling
Washington Convention Center, Room 143A/B
9:30 am - 12:00 noon
Chair:  Brian Kobilka, Stanford Univ.

Structural basis of biased agonism in GPCRs
  Xavier Deupi, Paul Scherrer Institute

Conformational adaptations and asymmetry in ligand binding and receptor activation
  Jean-Louis Baneres, Inst. des Biomolécules Max Mousseron, France

Molecular Electron Microscopy of Signaling Cell Surface Receptors
  Georgios Skiniotis, Univ. of Michigan

Drug Metabolism and Action in Pathophysiological Conditions
Washington Convention Center
9:30 am - 12:00 noon, Room 143C
Sponsored by the Divisions for Drug Metabolism; Integrative Systems, Translational & Clinical Pharmacology; and Toxicology
Chairs: R. Ghose, Univ. of Houston and E.T. Morgan, Emory Univ.

Overview and opening remarks
   Edward T. Morgan, Emory Univ

Altered expression of drug metabolizing enzymes and transporters in NAFLD
   Nathan Cherrington, Univ of Arizona College of Pharmacy

Effects of inflammation and its treatment on drug action and disposition
   Fakhreddin Jamali, Univ of Alberta

Regulation of drug metabolism in viral infections
   Maria Croyl, Univ of Texas at Austin College of Pharmacy

  Toll-like receptors:  Novel regulators of hepatic drug metabolizing enzymes
   Romi Ghose, Univ of Houston

Metabolism of midazolam is compromised in inflammation
   A. S. Ghandi,  Univ of Houston

Pharmacology for Healthcare Professionals: A Thirst for Knowledge
Grand Hyatt Hotel, Independence Ballroom H/I
9:30 am- 12:00 noon
Sponsored by the Divisions for Pharmacology Education; Cardiovascular Pharmacology; and Integrative Systems, Translational & Clinical Pharmacology
Chair: L. Wecker, Univ of South Florida

 Introduction to teaching pharmacology to health professionals
 Lynn Wecker, Univ of South Florida

Designing a pharmacology course for a doctor of physical therapy program
   Lynn Wecker, Univ of South Florida

A pharmacology course for physicians assistants
   Martha I. Davila-Garcia, Howard Univ

Pharmacology for undergraduate nursing programs
   Marshal Shlafer, Univ of Michigan

Pharmacology for the doctor of pharmacy curriculum
   Dan Kiel, Massachusetts College of Pharmacy and Health Sciences

A revised pharmacology curriculum for dental students
   Dennis Paul, Louisiana State Univ HSC, New Orleans

The Neurobiology of Post Traumatic Stress Disorder (PTSD) and Implications for Treatment
Washington Convention Center, Room 140 A
9:30 am - 12:00 noon
Sponsored by the Divisions for Behavioral Pharmacology and Integrative Systems, Translational & Clinical Pharmacology
Chairs: M. Davis, Emory Univ. and  L.L. Howell, Emory Univ.

Overview of the clinical problem of PTSD in the military
   Robert Ursano, Uniformed Services Univ for the Health Sciences

Neurochemical dysfunction in the single prolonged stress rodent model of PTSD
   Shane Perrine, Wayne State Univ

Stress-enhanced fear learning as a model of posttraumatic stress disorder
   Michael Fanselow, UCLA

Lack of safety signal learning in PTSD and role of NMDA receptors in fear extinction and psychotherapy
   Michael Davis, Emory Univ

D-cycloserine enhancement of exposure therapy in social anxiety

   Stefan Hofman, Boston Univ

Therapeutic Peptides: Novel Approaches in Drug Development
Washington Convention Center, Room 140B
9:30 am - 12:00 noon
Sponsored by the Divisions for Integrative Systems, Translational & Clinical Pharmacology; Cardiovascular Pharmacology; Drug Metabolism; and Toxicology
Chairs: S. Alagarsamy, Ferring Research Institute and M.A. Holinstat, Thomas Jefferson Univ.

Historical perspective of peptide therapeutics from bench to bedside
   Jens Peter Norgaard, Ferring Pharmaceut.

Guanylate Cyclase-C agonists: potential therapeutic agents for gastrointestinal disorders
   Mark Currie, Ironwood Pharmaceut.

Identification of novel peptides for tumor targeting and in-vivo imaging
   Jessica Crisp,  Univ of California, San Diego

Targeting receptors on the inside with pepducin technology
   Athan Kuliopulos, Tufts Univ. Sch. of Med.

The therapeutic potential of NT1 agonists in schizophrenia
   Joseph Goldberg, Univ of Illinois, Chicago