ASPET Short
Courses Introduction to Cardiac
Electrophysiology and Implications for Drug Development
April 3, 2005 (Held as a part of Experimental Biology '05)
Organizer: Benedict R.
Lucchesi Speakers:
Cardiac electrophysiology and arrhythmogenesis
Benedict R. Lucchesi, University of Michigan
Introduction to the electrocardiogram
Peter S. Fischbach, University of Michigan
Drug-induced malignant ventricular tachycardia (TdP): A
major safety pharmacology issue in drug selection, development and
registration
Icilio Cavero, Senior Research Advisor, Italy
Web Links
Lipid Signaling: Pathways and Paradigms
April 5, 2005 (Held as a part of Experimental Biology '05)
Organizers: Kathryn E.
Myer and Kevin R. Lynch
Speakers:
Phosphatidylcholine metabolism
Andrew J. Morris, Univ. of North Carolina at Chapel Hill
Phosphatidylinositol
metabolism
Michael Wakelam, Birmingham Univ. Med. Sch., Birmingham, UK
Sphingolipid metabolism
Alfred H. Merrill, Jr., Georgia Inst. of Tech.
Eicosanoid metabolism
Jilly Evans, Merck & Co.
A Beginner's Guide to
RNAi
April 20, 2004 (Held as a part of Experimental Biology '04)
Organizer: Michael T.
McManus Speakers:
Biology of RNA interference in mammals
Michael T. McManus, MIT
How to use siRNAs
Gyorgy Hutvagner, Univ. of Massachusetts Med. Sch.
How to make and use pol III hairpins
Dave Turner, Univ. of Michigan
How to make and package lentiviral RNAi vectors
Peter Sandy, MIT Web Links
RNAi protocols (siRNAs and
lentiviruses, etc)
http://web.mit.edu/mmcmanus/www/home1.2files/protocols.htm
http://web.mit.edu/mmcmanus/www/home1.2files/siRNAs.htm
http://web.mit.edu/ccrhq/vanparijs/pll37.htm
http://sitemaker.umich.edu/dlturner.vectors
Course on RNAi at MIT (key
publications)
http://web.mit.edu/mmcmanus/www/coursehome.htm
Additional RNAi publications
http://www.ambion.com/techlib/resources/RNAi/jclub.html
RNAi of the web (many links)
http://www.orbigen.com/RNAi_Orbigen.html
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