First Place: Jessica Bonzo, University of California San Diego. Advisor:
Robert Tukey  "Transgenic UDP-glucuronosyltransferase 1 mice are protected from obesity-induced type 2 diabetes."

Second Place: Dinesh Puppala, University of Kentucky. Advisor: Hollie Swanson "Inhibition of the aryl hydrocarbon receptor signaling pathway and cigarette smoke induced cell transformation by select dietary flavonoids."

First Place: Yonghong Zhao, University of Texas Medical Branch. Advisor:
Jim Halpert  "Conformational plasticity of cytochrome P450 2B4: crystallographic and solution studies."

Second Place: Xia Wen, Medical University of South Carolina. Advisor: Thomas Walle  "Methylation protects dietary flavonoids from rapid hepatic metabolism."

Chair-Elect: Kenneth Thummel, University of Washington, Seattle

Secretary/Treasurer-Elect: John Chiang, Northeastern Ohio University College of Medicine

Click HERE to see them

First Place: Mohamed A Abdelmegeed, Wayne State Univ.  Acetoacetate Inhibits Cytochrome P450 (CYP) 2E1 mRNA Through Suppression of Transcription and Induces CYP2E1 Protein Through Increased Translation and Decreased Protein Degradation in Primary Cultured Rat Hepatocytes. Advisor: Raymond F Novak 1

Second Place:  Xu Yang Univ of Washington Identification of 1α, 25-dihydroxyvitamin D3 as a novel endogenous substrate for cytochrome P450 3A4.  Advisor:  Kenneth E. Thummel 2

First Place:  Xiuling Zhang, New York State Dept of Health Variable Expression of CYP2A6 and CYP2A13 Proteins In Human Lung and Nasal Mucosa.  Advosor:   Xinxin Ding

Second Place:  Sanjoy Roychowdhury Univ of Iowa Visualization and quantification of intracellular protein adducts in human epidermal keratinocytes exposed to sulfamethoxazole (SMX) and dapsone (DDS). Advisor:  Craig K. Svensson

Chair-Elect: David S. Riddick, University of Toronto

Secretary/Treasurer-Elect: Xinxin Ding, Wadsworth Center, NYSDOH

First prize: Yen Weng, Department of Environmental Health and Toxicology, Wadsworth Center, School of Public Health, SUNY at Albany (Supervisor: Xinxin Ding), for the poster entitled “Microarray analysis of hepatic gene expression in liver-specific NADPH-cytochrome P450 reductase (Cpr)-knockout and global Cpr-knockdown mouse models.”
 

Second prize: Tiangan Li, Department of Biochemistry and Molecular Pathology, Northern Ohio Universities College of Medicine (supervisor: John Chiang), for the poster entitled “Lithocholic acid (LCA) inhibits human cholesterol 7-hydroxylase transcription via pregnane X receptor (PXR)-mediated pathway.”

First prize: Badanthadka Murali, Department of Toxicology, University of Louisiana at Monroe (Supervisor: Harihara Mehendale), for the poster entitled “Resistance of F344 rats to chlordecone-potentiated CCl4 hepatotoxicity and lethality is age-dependent.”
 

Second prize: Cheng Fang, Wadsworth Center, New York State Department of Health (Supervisor: Xinxin Ding), for the poster entitled “Preparation and initial characterization of a transgenic mouse model with forebrain-specific knockout of the NADPH-cytochrome P450 reductase (Cpr) gene.”

First prize:  Yannick Duguay, Université Laval (Supervisor: Chantal Guillemette), for the         poster entitled “UGT2B7: novel genomic variants in the promoter and functional consequences”.

Second prize:  Asmeen Jahan, Northeastern Ohio Universities College of Medicine (Supervisor: John Chiang), for the poster entitled “Suppression of the human sterol 12a-hydroxylase (CYP8B1) gene by interleukin-1ß”.

First prize:  Emily Scott, University of Texas Medical Branch (Supervisor: James Halpert), for the oral presentation entitled “Crystallization of a mammalian cytochrome P450 from the 2B subfamily”.

Second prize:  Santosh Kumar, University of Texas Medical Branch (Supervisor: James Halpert), for the oral presentation entitled “Engineering of cytochrome P450 2B1 for progesterone 21-hydroxylase activity”.

Chair-Elect: Timothy S. Tracy, University of Minnesota

Craig K. Svensson, University of Iowa