2008
Graduate Student Best Abstract Awards:
First Place: Steven Hart, University of
Kansas Medical Center. Advisor: Xiaobo Zhong. “Single nucleotide
polymorphisms in cytochrome P450 oxidoreductase influence drug
metabolism”
Second Place: Shuxin Han, Northeastern Ohio
Universities College of Medicine and Pharmacy. Advisor: John Chiang.
“Vitamin D receptor is expressed in human livers and inhibits CYP7A1
gene transcription”
2008
Postdoctoral Scientist Awards:
First Place: Chunshan Gui, University of
Kansas Medical Center. Advisor: Bruno Hagenbuch. “Molecular determinants
for substrate selectivity of OATP1B3”
Second Place: Ye Li, University of Kansas
Medical Center. Advisor: Xiaobo Zhong. “Genetic polymorphisms in the RNA
polymerase II core promoter and enhancer elements of the UGT1A1 promoter
influence activation of its gene transcription”
James
R. Gillette Drug Metabolism Best Papers of 2007
Metabolism category:
Senekeo-Effenberger K, Chen S, Brace-Sinnokrak E,
Bonzo JA, Yueh MF, Argikar U, Kaeding J, Trottier J, Remmel RP, Ritter
JK, Barbier O and Tukey TH. Expression of the human UGT1 locus in
transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic
acid (WY-14643) and implications on drug metabolism through peroxisome
proliferator-activated receptor alpha activation. Drug Metab Dispos
35:419-427, 2007.
Pharmacokinetics/Transporters category:
Shen H, Ocheltree SM, Hu Y, Keep RF and Smith DE.
Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics,
renal tubular reabsorption, and brain penetration in mice. Drug Metab
Dispos 35:1209-1216, 2007.
Seeking nominations for the 2009
Division for Drug Metabolism Early Career Achievement Award:
We are pleased to announce a call for nominations for the
next awarding of the ASPET Division for Drug Metabolism Early Career Achievement
Award. This biennial award will be presented for the second time at the
Experimental Biology ’09 meeting. It is anticipated that this award will become
a very important recognition of individuals’ contributions to the field of drug
metabolism and disposition during the early phases of their scientific careers.
Please give careful consideration to nominating a deserving individual prior to
the September 15, 2008 deadline.
Click here for more information.
2008 Election Results:
Chair-Elect: Jeffrey Stevens, Pfizer
Secretary/Treasurer-Elect: Michael Court, Tufts University School of
Medicine. Terms begin July 1, 2008
Division Meeting Minutes
2008
Bernard B. Brodie Award in Drug Metabolism:
