Lectures at ASPET's Centennial Meeting in San Diego
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Sunday, April 6, 9:00-11:30 AM, Convention Center Room 2
The G-Whizards Of GPCR/G-Protein Signaling
Chair: Lee E. Limbird
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- How the seed was sown: The interdependent evolution of the GPCR/G protein signaling field - LE Limbird (Meharry Med. Col.)
- Seven transmembrane receptors - RJ Lefkowitz (Duke Univ. Med. Ctr.)
- Receptor-catalyzed activation of heterotrimeric G proteins - HE Hamm (Vanderbilt Univ. Med. Ctr.)
- Where are we? - AG Gilman (Univ. of Texas Southwestern Med. Sch.)
Sunday, April 6, 9:00-11:30 AM, Convention Center Room 3
Julius Axelrod Symposium: Celebrating A Pioneer Pharmacologist And Hid Legacy: Creating New Drugs By Revealing Mechanisms Of Drug Action In Fundamental Biological Processes
Chair: Lee E. Eiden
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- A brief history of ASPET's Julius Axelrod Award and introduction of R. D. Blakely, recipient of the 2008 Julius Axelrod Award - DR Sibley (NINDS, NIH and Chair, ASPET Julius Axelrod Award Committee).
- Julie Axelrod: A legacy of fundamental research for drug discovery - LE Eiden (NIMH, NIH)
- Methylation pharmacogenomis: Neurotransmitters to drug response - RM Weinshilboum (Mayo Clin. Col. of Med.)
- Neurotransmitter transportres: New views of form and function - SG Amara (Univ. of Pittsburgh Sch. of Med.)
- Biochemical and behavioral actions of monoamines in genetic animal models - MG Caron (Duke Univ. Med. Ctr.)
Sunday, April 6, 2:30-5:00 PM, Convention Center Room 2
Chance Favors The Prepared Mind: A Nobel Perspective
Chair: Jeffrey S. Fedan
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- When you come to a fork in the road, take it - AG Gilman (Univ. of Texas Southwestern Med. Ctr.)
- The road to Stockholm - a Nobel mission - LJ Ignarro (UCLA Sch. of Med.)
Monday, April 7, 8:00 – 8:50 AM, Convention Center, Room 2
Ray Fuller Lecture: Broad Spectrum Antidepressants: Variations On A Monoamine Theme
Lecturer: Phil Skolnick, DOV Pharmaceuticals, Inc.
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Monday, April 7, 9:00 – 11:30 AM, Convention Center, Room 2
Ray Fuller Symposium: Antidepressants For The New Millennium: Circumventing The Monoamine Synapse
Chair: Phil Skolnick
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- The role of the NMDA receptor signaling cascade in antidepressant activity - IA Pau (Univ. of MIssissippi Med. Ctr.)
- AMPA receptor potentiation: A core antidepressant pathway? - JM Witkin (Eli Lilly and Co.)
- Potentiation of synaptic AMPA/NMDA mediated throughput in the development of novel therapeutics for
mood disorders - C Zarate (NIMH, NIH)
- Neurotrophic and neurogenic actions of antidepressants - H Schmidt (Yale Univ. Sch. of Med.)